Article
Association of DNA methylation in BDNF with escitalopram treatment response in depressed Chinese Han patients.
European journal of clinical pharmacology - 1 Aug 2018
Wang Peipei, Zhang Cuizhen, Lv Qinyu, Bao Chenxi, Sun Hong, Ma Guo, Fang Yiru, Yi Zhenghui, Cai Weimin
Abstract excerpt
PURPOSE: The neurotrophin brain-derived neurotrophic factor (BDNF) has been found to be associated with both the pathophysiology of depression and antidepressants response. Gene expression differences were partly mediated by SNP, which might be identified as a predictor of antidepressant response. In the present study, we attempt to identify whether DNA methylation, another factor known to affect gene...
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