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Article

Childhood adverse events and BDNF promoter methylation in later-life

24 Feb 2023

Abstract excerpt

Studies have shown that the effects of early-life stress and trauma can be enduring, with long-term negative effects on health. Epigenetics, including DNA methylation, have been implicated as a potential mechanism for these effects. Brain-derived neurotropic factor (BDNF) is a neurotransmitter involved in learning and memory, and altered BDNF promoter methylation measured in peripheral tissue has been found with...

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PMID: 36911114
DOI: 10.3389/fpsyt.2023.1108485

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