Article

Leveraging DNA Methylation to Predict Treatment Response in Major Depressive Disorder: A Critical Review

2023-12-02

Abstract excerpt

<h4>Background</h4> Major depressive disorder (MDD) is a debilitating and prevalent mental disorder with a high disease burden. Despite a wide array of different treatment options, many patients do not respond to initial treatment attempts. Selection of the most appropriate treatment remains a significant clinical challenge in psychiatry, highlighting the need for the development of biomarkers with predictive util...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a071d587-a3cb-5dca-8373-1c9d5dd0c358
DOI: 10.1101/2023.12.01.23299308

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Leveraging DNA Methylation to Predict Treatment Response in Major Depressive Disorder: A Critical ReviewDOI 10.1101/2023.12.01.23299308Read

Epigenetic profiles of response to transcranial magnetic stimulation in treatment resistant depressionSemantic proximity Read

Epigenome-Wide DNA Methylation in Unipolar Depression: Predictive Biomarker of Antidepressant Treatment Response?Semantic proximity Read

Epigenetic Signatures in Antidepressant Treatment Response: a Methylome-wide Association Study in the EMC TrialSemantic proximity Read

Dynamic Epigenetic Changes During Antidepressant Pharmacotherapy in Major Depressive DisorderSemantic proximity Read

Novel candidate genes for ECT response prediction—a pilot study analyzing the DNA methylome of depressed patients receiving electroconvulsive therapySemantic proximity Read

DNA Methylation of POMC and NR3C1-1F and Its Implication in Major Depressive Disorder and Electroconvulsive TherapySemantic proximity Read

DNA Methylation in Depression and Depressive-Like Phenotype: Biomarker or Target of Pharmacological Intervention?Semantic proximity Read

Serotonin Transporter Gene Promoter Hypomethylation as a Predictor of Antidepressant Treatment Response in Major Depression: A Replication StudySemantic proximity Read

P11 promoter methylation predicts the antidepressant effect of electroconvulsive therapySemantic proximity Read

Methylome-wide change associated with response to electroconvulsive therapy in depressed patientsSemantic proximity Read

Genomic predictors of response to antidepressants in Major depressive disorder (MDD): A GWAS-Based Study on Indian cohortSemantic proximity Read

DNA Methylation in Major Depressive Disorder.Semantic proximity Read