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BDNF Gene Polymorphism and Antidepressant Response in Han Chinese Patients with First-Episode Late-Life Depression

24 Apr 2025

Abstract excerpt

Objective: This study investigated the association between brain-derived neurotrophic factor (BDNF) gene polymorphisms and antidepressant response in patients with first-episode late-life depression (LLD). Methods: A total of 72 patients with first-episode LLD were recruited and 57 completed an 8-week course of antidepressant treatment. Participants were assessed at baseline and post-treatment using the 17-item...

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PMID: 40352065
DOI: 10.31083/ap39955

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