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Article

Increased activity of hypoxia-inducible factor 1 is associated with early embryonic lethality in Commd1 null mice.

Molecular and cellular biology - 1 Jun 2007

van de Sluis Bart, Muller Patricia, Duran Karen, Chen Amy, Groot Arjan J, Klomp Leo W, Liu Paul P, Wijmenga Cisca

Abstract excerpt

COMMD1 (previously known as MURR1) belongs to a novel family of proteins termed the copper metabolism gene MURR1 domain (COMMD) family. The 10 COMMD family members are well conserved between vertebrates, but the functions of most of the COMMD proteins are unknown. We recently established that COMMD1 is associated with the hepatic copper overload disorder copper toxicosis in Bedlington terriers. Recent in vitro...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17371845
DOI: 10.1128/MCB.01932-06
PMCID: PMC1900009

Genes

COMMD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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