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Article

FGFR1 actionable mutations, molecular specificities, and outcome of adult midline gliomas.

Neurology - 5 Jun 2018

Picca Alberto, Berzero Giulia, Bielle Franck, Touat Mehdi, Savatovsky Julien, Polivka Marc, Trisolini Elena, Meunier Sheida, Schmitt Yohann, Idbaih Ahmed, Hoang-Xuan Khe, Delattre Jean-Yves, Mokhtari Karima, Di Stefano Anna Luisa, Sanson Marc

Abstract excerpt

OBJECTIVE: To characterize the prevalence and prognostic significance of major driver molecular alterations in adult midline diffuse gliomas (MLG). METHODS: Adults with histologically proven MLG diagnosed between 1996 and 2017 were identified from our tumor bank, systematically reviewed, and reclassified according to WHO 2016. Targeted sequencing was performed, including determination of H3F3A, HIST1H3B, TERTp,...

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Share to DNA Modification Methylases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Isocitrate Dehydrogenase

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Share to Receptor, Fibroblast Growth Factor, Type 1

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Source

Identifiers

PMID: 29728520
DOI: 10.1212/WNL.0000000000005658

Genes

FGFR1
EGFR
IDH1
TERT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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