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Article

Diffuse Midline Gliomas With Histone H3 K27M Mutation in Adults and Children: A Retrospective Series of 164 Cases.

The American journal of surgical pathology - 1 Jun 2022

Zheng Linmao, Gong Jing, Yu Tianping, Zou Yan, Zhang Mengni, Nie Ling, Chen Xueqin, Yue Qiang, Liu Yanhui, Mao Qing, Zhou Qiao, Chen Ni

Abstract excerpt

Diffuse midline glioma, H3 K27M-mutant (H3 K27M-mt DMG), is a rare and highly aggressive tumor that is more common in children than in adults. Few studies have compared the differences between pediatric and adult patients with this rare tumor. We here report our retrospective study of 94 adult and 70 pediatric cases of diffuse midline glioma. Surgical tumor samples were analyzed by routine histopathology and...

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Identifiers

PMID: 35416795
DOI: 10.1097/PAS.0000000000001897
PMCID: PMC9093723

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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