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Article

Single-nucleotide polymorphisms of stemness genes predicted to regulate RNA splicing, microRNA and oncogenic signaling are associated with prostate cancer survival.

Carcinogenesis - 3 Jul 2018

Freedman Jennifer A, Wang Yanru, Li Xuechan, Liu Hongliang, Moorman Patricia G, George Daniel J, Lee Norman H, Hyslop Terry, Wei Qingyi, Patierno Steven R

Abstract excerpt

Prostate cancer (PCa) is a clinically and molecularly heterogeneous disease, with variation in outcomes only partially predicted by grade and stage. Additional tools to distinguish indolent from aggressive disease are needed. Phenotypic characteristics of stemness correlate with poor cancer prognosis. Given this correlation, we identified single-nucleotide polymorphisms (SNPs) of stemness-related genes and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29726910
DOI: 10.1093/carcin/bgy062
PMCID: PMC6248658

Genes

ABCC1
GDF15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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