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Article

Cancer Stem Cell Gene Variants Predict Disease Recurrence in Patients Treated with Radical Prostatectomy for Prostate Cancer.

International journal of medical sciences - 1 Jan 2017

Lin Victor C, Huang Shu-Pin, Huang Chao-Yuan, Yu Chia-Cheng, Yin Hsin-Ling, Huang Tsung-Yi, Lee Cheng-Hsueh, Lu Te-Ling, Bao Bo-Ying

Abstract excerpt

Background: Cancer stem cells (CSCs) are involved in tumor progression and drug resistance. We hypothesized that variants in CSC marker genes influence treatment outcomes in prostate cancer. Methods: Ten potentially functional single nucleotide polymorphisms (SNPs) in seven prostate CSC marker genes, TACSTD2, PROM1, ITGA2, POU5F1, EZH2, PSCA, and CD44, were selected for analysis of their association with disease...

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Identifiers

PMID: 29104488
DOI: 10.7150/ijms.21428
PMCID: PMC5666565

Genes

ITGA2
PROM1
PSCA
TACSTD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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