Article
A Splicing Transcriptome-Wide Association Study Identifies Candidate Altered Splicing for Prostate Cancer Risk.
Omics : a journal of integrative biology - 1 Aug 2023
Sun Yanfa, Bae Ye Eun, Zhu Jingjing, Zhang Zichen, Zhong Hua, Cheng Chunmei, Deng Youping, Wu Chong, Wu Lang
Abstract excerpt
Prostate cancer (PCa) represents a huge public health burden among men. Many susceptibility genetic factors for PCa still remain unknown. In this study, we performed a large splicing transcriptome-wide association study (spTWAS) using three modeling strategies to develop alternative splicing genetic prediction models for identifying novel susceptibility loci and splicing introns for PCa risk by assessing 79,194...
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