Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High copy number variations, particular transcription factors, and low immunity contribute to the stemness of prostate cancer cells

13 May 2021

Abstract excerpt

BACKGROUND: Tumor metastasis is the main cause of death of cancer patients, and cancer stem cells (CSCs) is the basis of tumor metastasis. However, systematic analysis of the stemness of prostate cancer cells is still not abundant. In this study, we explore the effective factors related to the stemness of prostate cancer cells by comprehensively mining the multi-omics data from TCGA database. METHODS: Based on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ferroptosis and cancer prognosis
Share to Prostate Cancer Treatment and Research
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33985534
DOI: 10.1186/s12967-021-02870-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High copy number variations, particular transcription factors, and low immunity contribute to the stemness of prostate cancer cellsPMID 33985534Read ↗

High copy number variations, particular transcription factors, and low immunity contribute to the stemness of prostate cancer cells.Semantic proximity Read ↗

Increasing Stemness Drives Prostate Cancer Progression, Plasticity, Therapy Resistance and Poor Patient SurvivalSemantic proximity Read ↗

The roots of cancer: Stem cells and the basis for tumor heterogeneitySemantic proximity Read ↗

Identification of Prostate Cancer Subtypes Based on Immune Signature Scores in Bulk and Single Cell TranscriptomesSemantic proximity Read ↗

The Molecular Biology of Prostate Cancer Stem Cells: From the Past to the FutureSemantic proximity Read ↗

Establishment of cancer-associated fibroblasts-related subtypes and prognostic index for prostate cancer through single-cell and bulk RNA transcriptomeSemantic proximity Read ↗

Integrative Analysis of Genes Associated With Cancer Stem Cell Characteristics via Stemness Indices Combined With Multi-Omics Data in Liver CancerSemantic proximity Read ↗

Prostate cancer as a dedifferentiated organ: androgen receptor, cancer stem cells, and cancer stemnessSemantic proximity Read ↗

Single-nucleotide polymorphisms of stemness genes predicted to regulate RNA splicing, microRNA and oncogenic signaling are associated with prostate cancer survival.Semantic proximity Read ↗

Concise Review: Prostate Cancer Stem Cells: Current UnderstandingSemantic proximity Read ↗

Integrated Bioinformatics Analysis Revealed Stemness Features and a Novel Stemness-Related Gene Signature for Risk Stratification in Pheochromocytomas and ParagangliomasSemantic proximity Read ↗

Circadian Rhythm Gene PER3 Negatively Regulates Stemness of Prostate Cancer Stem Cells via WNT/β-Catenin Signaling in Tumor MicroenvironmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.