Article
A common regulatory variant in SLC35B4 influences the recurrence and survival of prostate cancer.
Journal of cellular and molecular medicine - 1 Jul 2018
Huang Eric Y, Chang Yu-Jia, Huang Shu-Pin, Lin Victor C, Yu Chia-Cheng, Huang Chao-Yuan, Yin Hsin-Ling, Chang Ta-Yuan, Lu Te-Ling, Bao Bo-Ying
Abstract excerpt
Single nucleotide polymorphisms (SNPs) within the regulatory elements of a gene can alter gene expression, making these SNPs of prime importance for candidate gene association studies. We aimed to determine whether such regulatory variants are associated with clinical outcomes in three cohorts of patients with prostate cancer. We used RegulomeDB to identify potential regulatory variants based on in silico...
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