Article
HMGB1 genetic polymorphisms are biomarkers for the development and progression of breast cancer.
International journal of medical sciences - 1 Jan 2018
Huang Bi-Fei, Tzeng Huey-En, Chen Po-Chun, Wang Chao-Qun, Su Chen-Ming, Wang Yan, Hu Gui-Nv, Zhao Yong-Ming, Wang Qian, Tang Chih-Hsin
Abstract excerpt
Breast cancer is a major cause of cancer mortality worldwide. High-mobility group box protein 1 (HMGB1) is a ubiquitous nuclear protein found in all mammal eukaryotic cells that participates in tumor progression, migration and metastasis. HMGB1 overexpression has been indicated in breast cancer patients. However, scant information is available regarding the association between HMGB1 single nucleotide...
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