Article
Genetic predisposition of six well-defined polymorphisms in HMGB1/RAGE pathway to breast cancer in a large Han Chinese population.
Journal of cellular and molecular medicine - 1 Oct 2016
Yue Liling, Zhang Qibing, He Lan, Zhang Minglong, Dong Jing, Zhao Dalong, Ma Hongxing, Pan Hongming, Zheng Lihong
Abstract excerpt
Breast cancer constitutes an enormous burden in China. A strong familial clustering of breast cancer suggests a genetic component in its carcinogenesis. To examine the genetic predisposition of high mobility group box-1/receptor for advanced glycation end products (HMGB1/RAGE) pathway to breast cancer, we genotyped six well-defined polymorphisms in this pathway among 524 breast cancer patients and 518 cancer-free...
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