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Article

Exploratory Analysis of HMGB1 Genetic Variants and Their Potential Association with Lung Cancer Susceptibility and Chemotherapy Response in a Chinese Population.

Human heredity - 1 Jan 2026

Li Qing, Yan Li, Li Hongjing, Zhang Li, Li Quanxing, Yang Chunmei

Abstract excerpt

INTRODUCTION: High-mobility group box 1 (HMGB1) protein plays a significant role in cancer development and treatment response. The current research on the role of HMGB1 in lung cancer and its treatment outcomes is limited and inconsistent. This exploratory study investigated the association between HMGB1 common genetic variants and lung cancer susceptibility, as well as cisplatin chemotherapy response, in a...

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Identifiers

PMID: 41411212
DOI: 10.1159/000549745
PMCID: PMC12803519

Genes

HMGB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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