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Article

Akt2 modulates glucose availability and downstream apoptotic pathways during development.

The Journal of biological chemistry - 4 Jun 2010

Jensen Penny J, Gunter Laura B, Carayannopoulos Mary O

Abstract excerpt

Glucose is the primary energy substrate for eukaryotic cells and the predominant substrate for the brain. Studies suggest that glucose serves an additional role in the regulation of cellular functions, including viability. Zebrafish is a tractable system for defining the cellular and molecular mechanisms perturbed by impaired glucose transport and metabolism. Previously, we demonstrated a critical role for the...

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Share to Cell Survival
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Share to Gene Expression Regulation, Developmental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucose

Share to Glucose Transporter Type 1

Share to Microscopy, Fluorescence

Share to Proto-Oncogene Proteins c-akt

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Source

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Identifiers

PMID: 20356836
DOI: 10.1074/jbc.M109.079343
PMCID: PMC2878531

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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