Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness

1 May 2018

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related death. Therapeutic options remain very limited and are based on classical chemotherapies. Energy metabolism reprogramming appears as an emerging hallmark of cancer and is considered a therapeutic target with considerable potential. Myoferlin, a ferlin family member protein overexpressed in PDAC, is involved in plasma membrane...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diet and metabolism studies
Share to Metabolism, Diabetes, and Cancer
Share to Mitochondrial Function and Pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29720728
DOI: 10.1038/s41388-018-0287-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma, and affects tumor aggressivenessPMID 29720728Read ↗

Myoferlin Contributes to the Metastatic Phenotype of Pancreatic Cancer Cells by Enhancing Their Migratory Capacity through the Control of Oxidative PhosphorylationSemantic proximity Read ↗

Mutant p53 affects the mitochondrial proteome, promoting mitochondrial fragmentation and OXPHOS in pancreatic ductal adenocarcinoma cells.Semantic proximity Read ↗

Integrative study of skeletal muscle mitochondrial dysfunction in a murine pancreatic cancer-induced cachexia modelSemantic proximity Read ↗

MICAL2 Promotes Pancreatic Cancer Growth and MetastasisSemantic proximity Read ↗

The mitophagy effector FUNDC1 controls mitochondrial reprogramming and cellular plasticity in cancer cellsSemantic proximity Read ↗

NetrinG1+ Cancer-Associated Fibroblasts Generate Unique Extracellular Vesicles that Support the Survival of Pancreatic Cancer Cells Under Nutritional StressSemantic proximity Read ↗

NetrinG1 <sup>+</sup> cancer-associated fibroblasts generate unique extracellular vesicles that support the survival of pancreatic cancer cells under nutritional stressSemantic proximity Read ↗

PI5P4Kα Regulates Iron Balance to Promote Metabolic Fitness in Pancreatic CancerSemantic proximity Read ↗

Mitochondrial Fusion Suppresses Pancreatic Cancer Growth via Reduced Oxidative MetabolismSemantic proximity Read ↗

Targeting mitochondrial dysfunctions in pancreatic cancer evokes new therapeutic opportunitiesSemantic proximity Read ↗

iTRAQ-based quantitative proteomics reveals myoferlin as a novel prognostic predictor in pancreatic adenocarcinoma.Semantic proximity Read ↗

Deciphering the genomic and lncRNA landscapes of aerobic glycolysis identifies potential therapeutic targets in pancreatic cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.