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Article

Deciphering the genomic and lncRNA landscapes of aerobic glycolysis identifies potential therapeutic targets in pancreatic cancer.

International journal of biological sciences - 1 Jan 2021

Zhu Li-Li, Wu Zheng, Li Rong-Kun, Xing Xin, Jiang Yong-Sheng, Li Jun, Wang Ya-Hui, Hu Li-Peng, Wang Xu, Qin Wei-Ting, Sun Yong-Wei, Zhang Zhi-Gang, Yang Qin, Jiang Shu-Heng

Abstract excerpt

Aerobic glycolysis, also known as the Warburg effect, is emerged as a hallmark of most cancer cells. Increased aerobic glycolysis is closely associated with tumor aggressiveness and predicts a poor prognosis. Pancreatic ductal adenocarcinoma (PDAC) is characterized by prominent genomic aberrations and increased glycolytic phenotype. However, the detailed molecular events implicated in aerobic glycolysis of PDAC...

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Share to Carcinoma, Pancreatic Ductal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33390837
DOI: 10.7150/ijbs.49243
PMCID: PMC7757027

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