Article
Association of vitamin D with risk of type 2 diabetes: A Mendelian randomisation study in European and Chinese adults.
PLoS medicine - 1 May 2018
Lu Ling, Bennett Derrick A, Millwood Iona Y, Parish Sarah, McCarthy Mark I, Mahajan Anubha, Lin Xu, Bragg Fiona, Guo Yu, Holmes Michael V, Afzal Shoaib, Nordestgaard Børge G, Bian Zheng, Hill Michael, Walters Robin G, Li Liming, Chen Zhengming, Clarke Robert
Abstract excerpt
BACKGROUND: Observational studies have reported that higher plasma 25-hydroxyvitamin D (25[OH]D) concentrations are associated with lower risks of diabetes, but it is unclear if these associations are causal. The aim of this study was to test the relevance of 25(OH)D for type 2 diabetes using genetically instrumented differences in plasma 25(OH)D concentrations. METHODS AND FINDINGS: Data were available on four...
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