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Article

CYP2R1 (vitamin D 25-hydroxylase) gene is associated with susceptibility to type 1 diabetes and vitamin D levels in Germans.

Diabetes/metabolism research and reviews - 1 Nov 2007

Ramos-Lopez Elizabeth, Brück Patrick, Jansen Thomas, Herwig Jürgen, Badenhoop Klaus

Abstract excerpt

BACKGROUND: The vitamin D system has been implicated in type 1 diabetes by epidemiological and immune intervention studies as well as by polymorphisms of the vitamin D binding protein (DBP) and CYP27B1 genes. CYP2R1, a cytochrome P450 enzyme, catalyzes the formation of vitamin D3 to 25-hydroxyvitamin D3 (25(OH)D3), the main circulating vitamin D metabolite. METHODS: Two hundred and three simplex type 1 German...

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PMID: 17607662
DOI: 10.1002/dmrr.719

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DBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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