Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between circulating 25-hydroxyvitamin D and incident type 2 diabetes: a mendelian randomisation study.

The lancet. Diabetes & endocrinology - 1 Jan 2015

Ye Zheng, Sharp Stephen J, Burgess Stephen, Scott Robert A, Imamura Fumiaki, Langenberg Claudia, Wareham Nicholas J, Forouhi Nita G

Abstract excerpt

BACKGROUND: Low circulating concentrations of 25-hydroxyvitamin D (25[OH]D), a marker of vitamin D status, are associated with an increased risk of type 2 diabetes, but whether this association is causal remains unclear. We aimed to estimate the unconfounded, causal association between 25(OH)D concentration and risk of type 2 diabetes using a mendelian randomisation approach. METHODS: Using several data sources...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus, Type 2
Share to DBP gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DHCR7 gene

Share to Incidence

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Share to Vitamin D

Source

Open in PubMed Open full text

Identifiers

PMID: 25281353
DOI: 10.1016/S2213-8587(14)70184-6
PMCID: PMC4286815

Genes

DBP
DHCR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between circulating 25-hydroxyvitamin D and incident type 2 diabetes: a mendelian randomisation study.PMID 25281353Read ↗

Vitamin D concentration, obesity, and risk of diabetes: a mendelian randomisation study.Semantic proximity Read ↗

Association of vitamin D with risk of type 2 diabetes: A Mendelian randomisation study in European and Chinese adults.Semantic proximity Read ↗

Association of serum 25-hydroxyvitamin D with metabolic syndrome and type 2 diabetes: a one sample Mendelian randomization study.Semantic proximity Read ↗

Genetically Predicted Serum 25-Hydroxyvitamin D Concentrations in Related to Type 2 Diabetes Mellitus: A Mendelian Randomization Study.Semantic proximity Read ↗

A Bidirectional Mendelian Randomization Study to evaluate the causal role of reduced blood vitamin D levels with type 2 diabetes risk in South Asians and Europeans.Semantic proximity Read ↗

Mendelian randomisation studies of type 2 diabetes: future prospects.Semantic proximity Read ↗

Vitamin D and Type 1 Diabetes Risk: A Systematic Review and Meta-Analysis of Genetic Evidence.Semantic proximity Read ↗

Association of serum 25-hydroxyvitamin D levels, vitamin D-binding protein levels, and diabetes mellitus: Two-sample Mendelian randomization.Semantic proximity Read ↗

Association of Serum 25-Hydroxyvitamin D with Metabolic Syndrome and Type 2 Diabetes: A Mendelian Randomization StudySemantic proximity Read ↗

Inherited variation in vitamin D genes is associated with predisposition to autoimmune disease type 1 diabetes.Semantic proximity Read ↗

The Impact of Serum 25-hydroxyvitamin D, Calcium, and Parathyroid Hormone Levels on the Risk of Coronary Artery Disease in Patients With Diabetes: A Mendelian Randomization StudySemantic proximity Read ↗

Causal factors underlying diabetes risk informed by Mendelian randomisation analysis: evidence, opportunities and challengesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.