Article
Vitamin D concentration, obesity, and risk of diabetes: a mendelian randomisation study.
The lancet. Diabetes & endocrinology - 1 Apr 2014
Afzal Shoaib, Brøndum-Jacobsen Peter, Bojesen Stig E, Nordestgaard Børge G
Abstract excerpt
BACKGROUND: Low plasma 25-hydroxyvitamin D (25[OH]D) concentration and high BMI have been associated with increased risk of diabetes. We tested the hypotheses that genetic variants associated with low concentrations of 25(OH)D are associated with diabetes, and that the effect on diabetes of genetic variants associated with high BMI is partly mediated through reduced plasma 25(OH)D concentration. METHODS: In this...
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