Article
Vitamin D in Type 2 Diabetes: Genetic Susceptibility and the Response to Supplementation.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme - 1 Jul 2020
Klahold Edith, Penna-Martinez Marissa, Bruns Franziska, Seidl Christian, Wicker Sabine, Badenhoop Klaus
Abstract excerpt
Variants of vitamin D metabolism-genes may predispose to type 2 diabetes (T2D). This study investigated the impact of these variants on disease susceptibility, Vitamin D, parathyroid hormone, C-peptide and HbA1c levels before and after cholecalciferol supplementation in patients with T2D.Twelve polymorphisms within CYP2R1, CYP27B1, DBP, VDR and CYP24A1 were genotyped in 553 T2D patients and 916 controls. In...
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