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Article

Relapse pathway of glioblastoma revealed by single-cell molecular analysis.

Carcinogenesis - 3 Jul 2018

Chen Xuelian, Wen Qin, Stucky Andres, Zeng Yunjing, Gao Shengjia, Loudon William G, Ho Hector W, Kabeer Mustafa H, Li Shengwen Calvin, Zhang Xi, Zhong Jiang F

Abstract excerpt

Glioblastoma multiforme (GBM) remains an incurable brain tumor. The highly malignant behavior of GBM may, in part, be attributed to its intraclonal genetic and phenotypic diversity (subclonal evolution). Identifying the molecular pathways driving GBM relapse may provide novel, actionable targets for personalized diagnosis, characterization of prognosis and improvement of precision therapy. We screened single-cell...

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Identifiers

PMID: 29718126
DOI: 10.1093/carcin/bgy052
PMCID: PMC6248540

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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