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Glioblastoma heterogeneity at single cell resolution

5 Jun 2023

Abstract excerpt

Glioblastoma (GBM) is one of the deadliest types of cancer and highly refractory to chemoradiation and immunotherapy. One of the main reasons for this resistance to therapy lies within the heterogeneity of the tumor and its associated microenvironment. The vast diversity of cell states, composition of cells, and phenotypical characteristics makes it difficult to accurately classify GBM into distinct subtypes and...

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PMID: 37277603
DOI: 10.1038/s41388-023-02738-y

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