Article
How DNA lesions are turned into mutations within cells?
Oncogene - 16 Dec 2002
Pagès Vincent, Fuchs Robert P P
Abstract excerpt
Genomes of all living organisms are constantly injured by endogenous and exogenous agents that modify the chemical integrity of DNA and in turn challenge its informational content. Despite the efficient action of numerous repair systems that remove lesions in DNA in an error-free manner, some lesions, that escape these repair mechanisms, are present when DNA is being replicated. Although replicative DNA...
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