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Article

Repair and tolerance of DNA damage at the replication fork: A structural perspective.

Current opinion in structural biology - 1 Aug 2023

Eichman Brandt F

Abstract excerpt

The replication machinery frequently encounters DNA damage and other structural impediments that inhibit progression of the replication fork. Replication-coupled processes that remove or bypass the barrier and restart stalled forks are essential for completion of replication and for maintenance of genome stability. Errors in replication-repair pathways lead to mutations and aberrant genetic rearrangements and are...

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Identifiers

PMID: 37269798
DOI: 10.1016/j.sbi.2023.102618
PMCID: PMC10525001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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