Article
Biodistribution and Radiation Dosimetry of 124I-DPA-713, a PET Radiotracer for Macrophage-Associated Inflammation.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine - 1 Nov 2018
Foss Catherine A, Plyku Donika, Ordonez Alvaro A, Sanchez-Bautista Julian, Rosenthal Hailey B, Minn Il, Lodge Martin A, Pomper Martin G, Sgouros George, Jain Sanjay K
Abstract excerpt
Whole-body PET/CT was performed using 124I-DPA-713, a radioligand for the 18-kDa translocator protein (TSPO), to determine biodistribution and radiation dosimetry. Methods: Healthy subjects aged 18-65 y underwent whole-body PET/CT either at 4, 24, and 48 h or at 24, 48, and 72 h after intravenous injection of 124I-DPA-713. Time-activity curves were generated and used to calculate organ time-integrated activity...
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