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Article

VEGF signaling regulates the fate of obstructed capillaries in mouse cortex

24 Apr 2018

Abstract excerpt

Cortical capillaries are prone to obstruction, which over time, could have a major impact on brain angioarchitecture and function. The mechanisms that govern the removal of these obstructions and what long-term fate awaits obstructed capillaries, remains a mystery. We estimate that ~0.12% of mouse cortical capillaries are obstructed each day (lasting >20 min), preferentially in superficial layers and lower order...

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PMID: 29697373
DOI: 10.7554/elife.33670

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