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Article

Plasma biomarkers are associated with renal outcomes in individuals with APOL1 risk variants.

Kidney international - 1 Jun 2018

Nadkarni Girish N, Chauhan Kinsuk, Verghese Divya A, Parikh Chirag R, Do Ron, Horowitz Carol R, Bottinger Erwin P, Coca Steven G

Abstract excerpt

G1/G2 variants in the Apolipoprotein L1 (APOL1) gene are associated with end-stage renal disease (ESRD) in people with African ancestry. Plasma biomarkers may have utility for risk stratification in APOL1 high-risk individuals of African ancestry. To evaluate this, we measured tumor necrosis factor receptor 1/2 (TNFR1/2) and kidney injury molecule-1 (KIM1) in baseline plasma specimens from individuals of African...

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Source

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Identifiers

PMID: 29685497
DOI: 10.1016/j.kint.2018.01.026
PMCID: PMC5918426

Genes

APOL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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