Article
Epidemiology of transmitted drug resistance in chronically HIV-infected patients in Germany: the RESINA study 2001-2009.
Intervirology - 1 Jan 2012
Oette Mark, Reuter Stefan, Kaiser Rolf, Lengauer Thomas, Fätkenheuer Gerd, Knechten Heribert, Hower Martin, Pfister Herbert, Häussinger Dieter
Abstract excerpt
OBJECTIVES: Transmitted HIV drug resistance may impair treatment efficacy of combination antiretroviral therapy (ART). This study describes the epidemiology of transmitted resistance in chronically infected patients. METHODS: In a prospective multicenter trial in Nordrhein-Westfalen, Germany, transmitted drug resistance was determined by genotypic resistance testing in patients on initiation of first-line ART....
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