Article
Renal potassium handling in carriers of the Gly40Ser mutation of the glucagon receptor suggests a role for glucagon in potassium homeostasis.
Physiological reports - 1 Apr 2018
Bankir Lise, Barbato Antonio, Russo Ornella, Crambert Gilles, Iacone Roberto, Bouby Nadine, Perna Ludovica, Strazzullo Pasquale
Abstract excerpt
Plasma potassium concentration (PK ) is tightly regulated. Insulin is known to favor potassium entry into cells. But how potassium leaves the cells later on is not often considered. Previous studies in rats showed that glucagon infusion increased urinary potassium excretion dose-dependently and reversibly. This prompted us to investigate the possible influence of glucagon on potassium handling in humans. We took...
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