Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Is the renal kallikrein-kinin system a factor that modulates calciuria?

Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - 1 Jan 2000

Negri Armando Luis

Abstract excerpt

Renal tubular calcium reabsorption is one of the principal factors that determine serum calcium concentration and calcium excretion. Calcium excretion is regulated by the distal convoluted tubule and connecting tubule, where the epithelial calcium channel TRPV5 can be found, which limits the rate of transcellular calcium transport. The dynamic presence of the TRPV5 channel on the surface of the tubular cell is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcium
Share to Calcium Channels
Share to Cross-Over Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucuronidase

Share to Kidney Tubules, Distal

Share to Klotho Proteins

Share to Randomized Controlled Trials as Topic

Share to TRPV Cation Channels

Source

Identifiers

PMID: 27469036
DOI: 10.1016/j.nefro.2016.04.008

Genes

TRPV5

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Is the renal kallikrein-kinin system a factor that modulates calciuria?PMID 27469036Read ↗

Partial human genetic deficiency in tissue kallikrein activity and renal calcium handling.Semantic proximity Read ↗

Tissue kallikrein-deficient mice display a defect in renal tubular calcium absorption.Semantic proximity Read ↗

TRPV5 gene polymorphisms in renal hypercalciuria.Semantic proximity Read ↗

TRPV5: a Ca(2+) channel for the fine-tuning of Ca(2+) reabsorption.Semantic proximity Read ↗

Decreased calcium permeability caused by biallelic TRPV5 mutation leads to autosomal recessive renal calcium-wasting hypercalciuria.Semantic proximity Read ↗

Chronic nicotine exposure reduces klotho expression and triggers different renal and hemodynamic responses in klotho-haploinsufficient mice.Semantic proximity Read ↗

Partial genetic deficiency in tissue kallikrein impairs adaptation to high potassium intake in humans.Semantic proximity Read ↗

Physiology and pathophysiology of the calcium-sensing receptor in the kidney.Semantic proximity Read ↗

The role of transient receptor potential channels in kidney disease.Semantic proximity Read ↗

Klotho Prevents Renal Calcium LossSemantic proximity Read ↗

The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel.Semantic proximity Read ↗

Association of TRPV5, CASR, and CALCR genetic variants with kidney stone disease susceptibility in Egyptians through main effects and gene-gene interactions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.