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Article

Charting the unexplored extracellular matrix in cancer

1 Apr 2018

Abstract excerpt

The extracellular matrix (ECM) is present in all solid tissues and considered a master regulator of cell behaviour and phenotype. The importance of maintaining the correct biochemical and biophysical properties of the ECM, and the subsequent regulation of cell and tissue homeostasis, is illustrated by the simple fact that the ECM is highly dysregulated in many different types of disease, especially cancer. The...

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PMID: 29671911
DOI: 10.1111/iep.12269

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