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The extracellular matrix alteration, implication in modulation of drug resistance mechanism: friends or foes?

16 Sept 2022

Abstract excerpt

The extracellular matrix (ECM) is an important component of the tumor microenvironment (TME), having several important roles related to the hallmarks of cancer. In cancer, multiple components of the ECM have been shown to be altered. Although most of these alterations are represented by the increased or decreased quantity of the ECM components, changes regarding the functional alteration of a particular ECM...

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PMID: 36114508
DOI: 10.1186/s13046-022-02484-1

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