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Extracellular matrix remodeling in tumor progression and immune escape: from mechanisms to treatments

11 Mar 2023

Abstract excerpt

The malignant tumor is a multi-etiological, systemic and complex disease characterized by uncontrolled cell proliferation and distant metastasis. Anticancer treatments including adjuvant therapies and targeted therapies are effective in eliminating cancer cells but in a limited number of patients. Increasing evidence suggests that the extracellular matrix (ECM) plays an important role in tumor development through...

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PMID: 36906534
DOI: 10.1186/s12943-023-01744-8

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