ECM signalling: orchestrating cell behaviour and misbehaviour.

doi:10.1016/s0962-8924(98)01362-2

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Article

ECM signalling: orchestrating cell behaviour and misbehaviour.

Trends in cell biology - 1 Nov 1998

Lukashev M E, Werb Z

Abstract excerpt

The extracellular matrix (ECM) provides signalling cues that regulate cell behaviour and orchestrate functions of cells in tissue formation and homeostasis. The composition of the ECM, its three-dimensional organization and proteolytic remodelling are major determinants of the microenvironmental...

Topics

Animals
Extracellular Matrix
Humans
Phenotype
Retinoblastoma Protein
Signal Transduction
Tumor Suppressor Protein p53

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