Article
ECM signalling: orchestrating cell behaviour and misbehaviour.
Trends in cell biology - 1 Nov 1998
Lukashev M E, Werb Z
Abstract excerpt
The extracellular matrix (ECM) provides signalling cues that regulate cell behaviour and orchestrate functions of cells in tissue formation and homeostasis. The composition of the ECM, its three-dimensional organization and proteolytic remodelling are major determinants of the microenvironmental signalling context that controls cell shape, motility, growth, survival and differentiation. In recent years, the...
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