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Article

Knockout of glucose transporter GLUT6 has minimal effects on whole body metabolic physiology in mice.

American journal of physiology. Endocrinology and metabolism - 1 Aug 2018

Byrne Frances L, Olzomer Ellen M, Brink Robert, Hoehn Kyle L

Abstract excerpt

Glucose transporter 6 (GLUT6) is a member of the facilitative glucose transporter family. GLUT6 is upregulated in several cancers but is not widely expressed in normal tissues. Previous studies have shown that GLUT6 knockdown kills endometrial cancer cells that express elevated levels of the protein. However, whether GLUT6 represents a viable anticancer drug target is unclear because the role of GLUT6 in normal...

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Identifiers

PMID: 29664675
DOI: 10.1152/ajpendo.00082.2018

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