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Article

Slc2a8 deficiency in mice results in reproductive and growth impairments.

Biology of reproduction - 1 Aug 2012

Adastra Katie L, Frolova Antonina I, Chi Maggie M, Cusumano Daniel, Bade Mary, Carayannopoulos Mary O, Moley Kelle H

Abstract excerpt

SLC2A8, also known as GLUT8, is a facilitative glucose transporter expressed in the testis, brain, liver, heart, uterus, ovary, and fat. In this study we examined the effect of Slc2a8 deficiency on mouse gamete, preimplantation embryo, and implantation phenotype, as well as postnatal growth and physiology. For this model, the transcriptional start site and exons 1-4 were targeted and a lack of protein expression...

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Source

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Identifiers

PMID: 22649075
DOI: 10.1095/biolreprod.111.097675
PMCID: PMC3431428

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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