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Article

A Nonsynonymous Variant in the GOLM1 Gene in Cutaneous Malignant Melanoma.

Journal of the National Cancer Institute - 1 Dec 2018

Teerlink Craig C, Huff Chad, Stevens Jeff, Yu Yao, Holmen Sheri L, Silvis Mark R, Trombetti Kirby, Zhao Hua, Grossman Douglas, Farnham James M, Wen Jingran, Facelli Julio C, Thomas Alun, Babst Markus, Florell Scott R, Meyer Laurence, Zone John J, Leachman Sancy, Cannon-Albright Lisa A

Abstract excerpt

Background: Statistically significant linkage of melanoma to chromosome 9q21 was previously reported in a Danish pedigree resource and independently confirmed in Utah high-risk pedigrees, indicating strong evidence that this region contains a melanoma predisposition gene. Methods: Whole-exome sequencing of pairs of related melanoma case subjects from two pedigrees with evidence of 9q21 linkage was performed to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29659923
DOI: 10.1093/jnci/djy058
PMCID: PMC6292789

Genes

GOLM1

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