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Article

Genetic analysis of the GRM1 gene in human melanoma susceptibility.

European journal of human genetics : EJHG - 1 Nov 2007

Ortiz Pablo, Vanaclocha Francisco, López-Bran Eduardo, Esquivias José Ignacio, López-Estebaranz José Luis, Martín-González Manuel, Arrue Itziar, García-Romero Diana, Ochoa Carolina, González-Perez Antonio, Ruiz Agustin, Real Luis Miguel

Abstract excerpt

Data obtained from a mouse model indicated that the ectopic expression of the Grm1 gene is sufficient for transforming melanocytes and causing malignant melanoma in vivo. In addition, it has also been documented that the GRM1 gene is aberrantly expressed in human melanomas. Here we have performed...

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Identifiers

PMID: 17609672
DOI: 10.1038/sj.ejhg.5201887

Genes

GRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17609672-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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