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Article

Blood pressure and risk of incident Alzheimer's disease dementia by antihypertensive medications and APOE ε4 allele.

Annals of neurology - 1 May 2018

Rajan Kumar B, Barnes Lisa L, Wilson Robert S, Weuve Jennifer, McAninch Elizabeth A, Evans Denis A

Abstract excerpt

OBJECTIVE: To examine the association of blood pressure (BP) with incident Alzheimer's disease (AD) dementia. METHODS: This work is based on a longitudinal, cohort study of 18 years, the Chicago Health and Aging Project (CHAP) performed in 2,137 participants (55% black) with systolic BP measured around 8.1 years before incident AD dementia. RESULTS: The association of BP with risk of AD dementia was U-shaped,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29637601
DOI: 10.1002/ana.25228
PMCID: PMC6149540

Genes

APOE
DBP

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