Back to search

Article

Effect of initiating an ARB- versus ACEI-based regimen on dementia risk, a target trial emulation of 2.5 million US Veterans

2026-07-08

Abstract excerpt

<h4>Background: </h4> Hypertension is a modifiable risk factor for dementia, yet the comparative effectiveness of angiotensin receptor blockers (ARBs) versus angiotensin converting enzyme inhibitors (ACEIs) on dementia risk remains uncertain. <h4>Objective:</h4> To compare the risk of dementia and dementia-free death of ARB versus ACEI initiation among US Veterans with incident hypertension. <h4>Methods:</h4> We c...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
756731e8-712c-5c11-9a4f-3764b70bd5ee
DOI
10.64898/2026.07.05.26357173
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Effect of initiating an ARB- versus ACEI-based regimen on dementia risk, a target trial emulation of 2.5 million US VeteransDOI 10.64898/2026.07.05.26357173
Exposure to angiotensin-converting enzyme inhibitors that cross the blood-brain barrier and the risk of dementia among patients with human immunodeficiency virusSemantic proximity
Repurposing drugs for the prevention of vascular dementia: Evidence from drug target Mendelian randomizationSemantic proximity
Concurrent Gabapentin and Dihydropyridine Calcium Channel Blocker Use and Risk of Incident Dementia: An Active-Comparator Cohort StudySemantic proximity
Low-Density Lipoprotein Cholesterol and Dementia Risk: Integrating Mendelian Randomization and Target Trial Emulation Within the Heart–Brain AxisSemantic proximity
Glucagon-like peptide-1 receptor agonist initiation and risk of clinically recorded Alzheimer's disease-type dementia in older adults with type 2 diabetes: a target trial emulation using causal machine learningSemantic proximity
Population‐based discovery and Mendelian randomization analysis identify telmisartan as a candidate medicine for Alzheimer's disease in African AmericansSemantic proximity
Causal cardiovascular risk factors for dementia: insights from observational and genetic studies.Semantic proximity
Identifying incident dementia by applying machine learning to a very large administrative claims datasetSemantic proximity
Class-Specific Antihypertensives and Alzheimer's Disease: Genotype- and Hypertension-Stratified Analysis.Semantic proximity
Combination therapies delay cognitive decline over 10 years in Alzheimer’s NACC participantsSemantic proximity
Blood pressure and risk of incident Alzheimer's disease dementia by antihypertensive medications and APOE ε4 allele.Semantic proximity
Hormone replacement therapy and dementia risk among postmenopausal women: evidence from the UK BiobankSemantic proximity
Select a neighboring publication to make it the new centre.