Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Combined effects of APOE genotype, blood pressure, and antihypertensive drug use on incident AD.

Neurology - 9 Sept 2003

Qiu Chengxuan, Winblad Bengt, Fastbom Johan, Fratiglioni Laura

Abstract excerpt

OBJECTIVE: To study the hypotheses that APOE-epsilon4 allele may interact with blood pressure to affect Alzheimer's disease (AD) occurrence and that antihypertensive therapy could modify such an effect. METHODS: A dementia-free cohort of 966 community-dwelling persons aged 75 years and older in Stockholm, Sweden was followed to detect patients with AD using the Diagnostic and Statistical Manual of Mental...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Antihypertensive Agents
Share to Apolipoprotein E4

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Apolipoproteins E

Share to Blood Pressure

Share to Follow-Up Studies

Share to Incidence

Share to Sweden

Source

Identifiers

PMID: 12963757
DOI: 10.1212/wnl.61.5.655

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Combined effects of APOE genotype, blood pressure, and antihypertensive drug use on incident AD.PMID 12963757Read ↗

Apolipoprotein E genotypes and the incidence of Alzheimer's disease among persons aged 75 years and older: variation by use of antihypertensive medication?Semantic proximity Read ↗

Blood pressure and risk of incident Alzheimer's disease dementia by antihypertensive medications and APOE ε4 allele.Semantic proximity Read ↗

Antihypertensive medication is associated with less cognitive impairment in the very old with apolipoprotein-E epsilon4 allele.Semantic proximity Read ↗

The association between APOE and dementia does not seem to be mediated by vascular factors.Semantic proximity Read ↗

[Vascular risk factors and Alzheimer disease risk: epidemiological studies review].Semantic proximity Read ↗

Hypertension, a dementia polygenic risk score, APOE genotype, and incident dementia.Semantic proximity Read ↗

Class-Specific Antihypertensives and Alzheimer's Disease: Genotype- and Hypertension-Stratified Analysis.Semantic proximity Read ↗

Epsilon 4 allele of apolipoprotein E gene associates with lower blood pressure in young Japanese subjects: the Suita Study.Semantic proximity Read ↗

Enhanced risk for Alzheimer disease in persons with type 2 diabetes and APOE epsilon4: the Cardiovascular Health Study Cognition Study.Semantic proximity Read ↗

Joint effect of hypertension and APOE genotype on CSF biomarkers for Alzheimer's disease.Semantic proximity Read ↗

Angiotensin converting enzyme inhibitors and Alzheimer disease in the presence of the apolipoprotein E4 allele.Semantic proximity Read ↗

Blood pressure interacts with APOE ε4 to predict memory performance in a midlife sample.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.