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Article

Associations of Pulse and Blood Pressure with Hippocampal Volume by APOE and Cognitive Phenotype: The Alzheimer's Disease Neuroimaging Initiative (ADNI).

Dementia and geriatric cognitive disorders - 1 Jan 2018

Ngwa Julius S, Fungwe Thomas V, Ntekim Oyonumo, Allard Joanne S, Johnson Sheree M, Castor Chimene, Graham Lennox, Nadarajah Sheeba, Gillum Richard F, Obisesan Thomas O

Abstract excerpt

BACKGROUND: It is increasingly evident that high blood pressure can promote reduction in global and regional brain volumes. While these effects may preferentially affect the hippocampus, reports are inconsistent. METHODS: Using data from the Alzheimer's Disease Neuroimaging Initiative (ADNI), we examined the relationships of hippocampal volume to pulse pressure (PPR) and systolic (SBP) and diastolic (DBP) blood...

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Source

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Identifiers

PMID: 29694964
DOI: 10.1159/000486955
PMCID: PMC6143389

Genes

APOE
DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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