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Article

New Methods for Inferring the Distribution of Fitness Effects for INDELs and SNPs.

Molecular biology and evolution - 1 Jun 2018

Barton Henry J, Zeng Kai

Abstract excerpt

Small insertions and deletions (INDELs; ≤50 bp) are the most common type of variability after single nucleotide polymorphism (SNP). However, compared with SNPs, we know little about the distribution of fitness effects (DFE) of new INDEL mutations and how prevalent adaptive INDEL substitutions are. Studying INDELs has been difficult partly because identifying ancestral states at these sites is error-prone and...

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Identifiers

PMID: 29635416
DOI: 10.1093/molbev/msy054
PMCID: PMC5967470

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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