Article
Role of toll-interacting protein gene polymorphisms in leprosy Mexican patients.
BioMed research international - 1 Jan 2013
Montoya-Buelna Margarita, Fafutis-Morris Mary, Tovar-Cuevas Alvaro J, Alvarado-Navarro Anabell, Valle Yeminia, Padilla-Gutierrez Jorge R, Muñoz-Valle Jose F, Figuera-Villanueva Luis E
Abstract excerpt
BACKGROUND: Leprosy is a debilitating infectious disease of human skin and nerves. Genetics factors of the host play an important role in the disease susceptibility. Toll-interacting protein (TOLLIP) is an inhibitory adaptor protein within the toll-like receptor (TLR) pathway, which recognizes structurally conserved molecular patterns of microbial pathogens, initiating immune responses. The objective of this...
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