Article
Cooperation of Rho family proteins Rac1 and Cdc42 in cartilage development and calcified tissue formation.
Biochemical and biophysical research communications - 7 Jun 2018
Ikehata Mikiko, Yamada Atsushi, Fujita Koji, Yoshida Yuko, Kato Tadashi, Sakashita Akiko, Ogata Hiroaki, Iijima Takehiko, Kuroda Masahiko, Chikazu Daichi, Kamijo Ryutaro
Abstract excerpt
Rac1 and Cdc42, Rho family low molecular weight G proteins, are intracellular signaling factors that transmit various information from outside to inside cells. Primarily, they are known to control various biological activities mediated by actin cytoskeleton reorganization, such as cell proliferation, differentiation, and apoptosis. In order to investigate the functions of Rac1 and Cdc42 in bone formation, we...
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