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Article

ApoE4 May be a Promising Target for Treatment of Coronary Heart Disease and Alzheimer's Disease.

Current drug targets - 1 Jan 2018

Chen Wei, Jin Fengzhong, Cao Guihua, Mei Rong, Wang Yayun, Long Pan, Wang Xiaoming, Ge Wei

Abstract excerpt

Alzheimer disease (AD) is most common neurodegenerative disorder of dementia, as we all know that ApoE4 is the greatest genetic risk factor of late-onset Alzheimer's disease (LOAD). Coronary heart disease (CHD) leads to one-fourth of all deaths in industrialized countries, it is reported that ApoE4 increases the risk of coronary heart disease as well. Furthermore, evidence show that coronary heart disease also...

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Identifiers

PMID: 29623835
DOI: 10.2174/1389450119666180406112050

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