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Article

Determining Genotypic Drug Resistance by Ion Semiconductor Sequencing With the Ion AmpliSeq™ TB Panel in Multidrug-Resistant Mycobacterium tuberculosis Isolates.

Annals of laboratory medicine - 1 Jul 2018

Park Joonhong, Shin So Youn, Kim Kyungjong, Park Kuhn, Shin Soyoung, Ihm Chunhwa

Abstract excerpt

BACKGROUND: We examined the feasibility of a full-length gene analysis for the drug resistance-related genes inhA, katG, rpoB, pncA, rpsL, embB, eis, and gyrA using ion semiconductor next-generation sequencing (NGS) and compared the results with those obtained from conventional phenotypic drug susceptibility testing (DST) in multidrug-resistant Mycobacterium tuberculosis (MDR-TB) isolates. METHODS: We extracted...

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Identifiers

PMID: 29611381
DOI: 10.3343/alm.2018.38.4.316
PMCID: PMC5895860

Genes

DST
EMB

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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